The scales and tales of myelination: using zebrafish and mouse to study myelinating glia.

Abstract

Myelin, the lipid-rich sheath that insulates axons to facilitate rapid conduction of action potentials, is an evolutionary innovation of the jawed-vertebrate lineage. Research efforts aimed at understanding the molecular mechanisms governing myelination have primarily focused on rodent models; however, with the advent of the zebrafish model system in the… (More)
DOI: 10.1016/j.brainres.2015.10.011

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