The scaffold protein Ste5 directly controls a switch-like mating decision in yeast

@article{Malleshaiah2010TheSP,
  title={The scaffold protein Ste5 directly controls a switch-like mating decision in yeast},
  author={Mohan K. Malleshaiah and Vahid Shahrezaei and Peter S. Swain and Stephen W. Michnick},
  journal={Nature},
  year={2010},
  volume={465},
  pages={101-105}
}
Evolution has resulted in numerous innovations that allow organisms to increase their fitness by choosing particular mating partners, including secondary sexual characteristics, behavioural patterns, chemical attractants and corresponding sensory mechanisms. The haploid yeast Saccharomyces cerevisiae selects mating partners by interpreting the concentration gradient of pheromone secreted by potential mates through a network of mitogen-activated protein kinase (MAPK) signalling proteins. The… CONTINUE READING

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