The scaffold protein RACK1 is a target of endocrine disrupting chemicals (EDCs) with important implication in immunity.

@article{Buoso2017TheSP,
  title={The scaffold protein RACK1 is a target of endocrine disrupting chemicals (EDCs) with important implication in immunity.},
  author={Erica Buoso and Marilisa Galasso and Melania Ronfani and Angela Papale and Valentina Galbiati and Ivano Eberini and Marina Marinovich and Marco Racchi and Emanuela Corsini},
  journal={Toxicology and applied pharmacology},
  year={2017},
  volume={325},
  pages={37-47}
}
We recently demonstrated the existence of a complex hormonal balance between steroid hormones in the control of RACK1 (Receptor for Activated C Kinase 1) expression and immune activation, suggesting that this scaffold protein may also be targeted by endocrine disrupting chemicals (EDCs). As a proof of concept, we investigated the effect of the doping agent… CONTINUE READING