The sarcomeric Z-disc component myopodin is a multiadapter protein that interacts with filamin and alpha-actinin.

@article{Linnemann2010TheSZ,
  title={The sarcomeric Z-disc component myopodin is a multiadapter protein that interacts with filamin and alpha-actinin.},
  author={Anja Linnemann and Peter F. M. van der Ven and Padmanabhan Vakeel and Britta Albinus and Dirk Simonis and Gerd Bendas and J{\"o}rg A. Schenk and Burkhard Micheel and Rudolf Andr{\'e} Kley and Dieter O. F{\"u}rst},
  journal={European journal of cell biology},
  year={2010},
  volume={89 9},
  pages={681-92}
}
Here we introduce myopodin as a novel filamin C binding partner. Corroborative yeast two-hybrid and biochemical analyses indicate that the central part of myopodin that shows high homology to the closely related protein synaptopodin and that is common to all its currently known or predicted variants interacts with filamin C immunoglobulin-like domains 20-21. A detailed characterization of the previously described interaction between myopodin and alpha-actinin demonstrates for the first time… CONTINUE READING
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