The safety of statins in clinical practice

@article{Armitage2007TheSO,
  title={The safety of statins in clinical practice},
  author={Jane Armitage},
  journal={The Lancet},
  year={2007},
  volume={370},
  pages={1781-1790}
}
  • Jane Armitage
  • Published 2007
  • Medicine
  • The Lancet
  • Statins are effective cholesterol-lowering drugs that reduce the risk of cardiovascular disease events (heart attacks, strokes, and the need for arterial revascularisation). Adverse effects from some statins on muscle, such as myopathy and rhabdomyolysis, are rare at standard doses, and on the liver, in increasing levels of transaminases, are unusual. Myopathy--muscle pain or weakness with blood creatine kinase levels more than ten times the upper limit of the normal range--typically occurs in… CONTINUE READING

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