The safety assessment of fragrance materials.
@article{Bickers2003TheSA, title={The safety assessment of fragrance materials.}, author={David R. Bickers and Peter Calow and Helmut Greim and Jon Hanifin and Adrianne E. Rogers and Jean Hilaire Saurat and I Glenn Sipes and Robert L. Smith and Hachiro Tagami}, journal={Regulatory toxicology and pharmacology : RTP}, year={2003}, volume={37 2}, pages={ 218-73 } }
Figures and Tables from this paper
102 Citations
Criteria for the Research Institute for Fragrance Materials, Inc. (RIFM) safety evaluation process for fragrance ingredients.
- Environmental ScienceFood and chemical toxicology : an international journal published for the British Industrial Biological Research Association
- 2015
Subject Area 7 – Risk Assessment , Risk Management , Health Issues Fragrances in the Environment : Pleasant Odours for Nature ? *
- Environmental Science
- 2007
Goal, Scope and Background. Fragrance preparations or perfumes are used in an increasing variety of applications, as for example washing, cleansing, personal care products, consumer goods or in…
Application of the threshold of toxicological concern (TTC) to the safety evaluation of cosmetic ingredients.
- Environmental ScienceFood and chemical toxicology : an international journal published for the British Industrial Biological Research Association
- 2007
RIFM low-exposure fragrance ingredients safety assessment.
- Environmental ScienceFood and chemical toxicology : an international journal published for the British Industrial Biological Research Association
- 2021
Fragrances in the Environment: Pleasant odours for nature? (9 pp)
- Environmental ScienceEnvironmental science and pollution research international
- 2007
The interdisciplinary approach, bringing together chemical, biological, toxicological and ecotoxicological data with information provided by manufacturers and with legal and consumer aspects, offers new insights into the field of fragrance substances used in consumer products.
Risk management by labelling 26 fragrances? Evaluation of Article 10 (1) of the seventh Amendment (Guideline 2003/15/EC) of the Cosmetic Directive.
- BusinessInternational journal of hygiene and environmental health
- 2010
Macrocyclic fragrance materials--a screening-level environmental assessment using chemical categorization.
- Environmental ScienceEcotoxicology and environmental safety
- 2011
Identification of potential PBT behavior of personal care products by structural approaches
- Chemistry
- 2015
Peroxide levels along the fragrance value chain comply with IFRA standards
- Environmental Science
- 2015
Autoxidation of certain perfume ingredients can result in the formation of sensitizing chemicals although the parent compounds are non-sensitizing. Peroxide values were determined for 875 freshly…
Determination of fragrance allergens in indoor air by active sampling followed by ultrasound-assisted solvent extraction and gas chromatography-mass spectrometry.
- Environmental ScienceJournal of chromatography. A
- 2010
References
SHOWING 1-10 OF 57 REFERENCES
Criteria for development of a database for safety evaluation of fragrance ingredients.
- Materials ScienceRegulatory toxicology and pharmacology : RTP
- 2000
This approach, specifically considering the dermal route of exposure as the most relevant one for fragrance ingredients, has been developed and is designed to be conservative but not so much so as to require excessive effort when not justified.
A framework for prioritizing fragrance materials for aquatic risk assessment
- Environmental ScienceEnvironmental toxicology and chemistry
- 2002
These combined exercises demonstrated the ability of this highly precautionary risk-based screening approach to quickly prioritize a large number of materials without benefit of experimental ecotoxicological or fate data.
Consumer exposure to fragrance ingredients: providing estimates for safety evaluation.
- Environmental ScienceRegulatory toxicology and pharmacology : RTP
- 2002
Estimates of exposure through different routes and leading to different potential endpoints indicate that deposition on the surface of the skin following use of cosmetics represents the major route of exposure to fragrance ingredients when conservative estimates for evaporation, rinsing, and other forms of product removal are employed.
Environmental risk assessment of musk ketone and musk xylene in The Netherlands in accordance with the EU-TGD.
- Environmental ScienceChemosphere
- 1997
Sensitization Methodology and Primary Prevention of the Research Institute for Fragrance Materials
- MedicineDermatology
- 2002
In subjects where sensitization was induced by predictive testing, no serious recurring adverse dermatological conditions developed and most subjects were able to use a bar soap, a moisurizing lotion and cologne-type products with up to 1% hydroxycitronellal.
The FEMA GRAS assessment of alicyclic substances used as flavour ingredients.
- Chemistry, MedicineFood and chemical toxicology : an international journal published for the British Industrial Biological Research Association
- 1996
The importance of exposure estimation in the assessment of skin sensitization risk
- MedicineContact dermatitis
- 2000
The critical exposure determinant for evaluating skin sensitization risk is dose per unit area of skin exposed, and, at least for known potent allergens, there is remarkable similarity in threshold dose/unit area determinations across species.
Understanding fragrance allergy using an exposure‐based risk assessment approach
- MedicineContact dermatitis
- 2001
By estimating the exposure to the allergen and its allergenic potency, it is feasible to assess quantitatively the sensitization risk of an ingredient in a particular product type.
Environmental risk assessment for the polycyclic musks, AHTN and HHCB. II. Effect assessment and risk characterisation.
- Environmental ScienceToxicology letters
- 1999
The Epidemiology of Fragrance Allergy: Questions and Needs
- MedicineDermatology
- 2002
Both a ‘sentinel surveillance’ system and more refined epidemiological studies in well-defined populations are needed to reliably assess the risks associated with fragrance exposure and risk assessment requires that data from different sources are integrated and compared.