The safety and effectiveness of remifentanil as an adjunct sedative for regional anesthesia.

@article{Lauwers1999TheSA,
  title={The safety and effectiveness of remifentanil as an adjunct sedative for regional anesthesia.},
  author={Marie Hel{\'e}ne Lauwers and Fr{\'e}d{\'e}ric Camu and Harald Petter Breivik and Annika Hagelberg and M{\aa}ns Ros{\'e}n and Robert Sneyd and Arild Horn and D C Noronha and Soraya Shaikh},
  journal={Anesthesia and analgesia},
  year={1999},
  volume={88 1},
  pages={134-40}
}
UNLABELLED We assessed the sedative potential of continuous infusions of remifentanil with a validated composite alertness scale in 160 patients (ASA physical status I or II) undergoing hip replacement surgery with spinal block (n = 61) or hand surgery using brachial plexus block (n = 93). They were randomized to receive one of the following initial dose regimens in double-blinded fashion: placebo or 0.04, 0.07, or 0.1 microg x kg(-1) x min(-1) remifentanil subsequently titrated to effect… CONTINUE READING