The rox1 and rox2 RNAs are essential components of the compensasome, which mediates dosage compensation in Drosophila.

@article{Franke1999TheRA,
  title={The rox1 and rox2 RNAs are essential components of the compensasome, which mediates dosage compensation in Drosophila.},
  author={Axel Franke and Bruce S. Baker},
  journal={Molecular cell},
  year={1999},
  volume={4 1},
  pages={117-22}
}
The rox1 and rox2 RNAs have been suggested to be components of the dosage compensation machinery in Drosophila. We show that both rox RNAs colocalize with the male-specific lethal proteins at hundreds of specific bands along the male X chromosome. The rox RNAs and MSL proteins also colocalize with the X chromosome in all somatic cells and are expressed in the same temporal pattern throughout development. Genetic analysis shows that the functions of the rox genes are redundant and required for… CONTINUE READING

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