The roles played by Aspergillus nidulans apoptosis-inducing factor (AIF)-like mitochondrial oxidoreductase (AifA) and NADH-ubiquinone oxidoreductases (NdeA-B and NdiA) in farnesol resistance.

@article{Dinamarco2010TheRP,
  title={The roles played by Aspergillus nidulans apoptosis-inducing factor (AIF)-like mitochondrial oxidoreductase (AifA) and NADH-ubiquinone oxidoreductases (NdeA-B and NdiA) in farnesol resistance.},
  author={Ta{\'i}sa Magnani Dinamarco and B{\'a}rbara de Castro Figueiredo Pimentel and Marcela Savoldi and Iran Malavazi and Frederico M. Soriani and S{\'e}rgio Akira Uyemura and Paula Ludovico and Maria Helena de Souza Goldman and Gustavo Henrique Goldman},
  journal={Fungal genetics and biology : FG & B},
  year={2010},
  volume={47 12},
  pages={1055-69}
}
Farnesol (FOH) is a nonsterol isoprenoid produced by dephosphorylation of farnesyl pyrophosphate, a catabolite of the cholesterol biosynthetic pathway. These isoprenoids inhibit proliferation and induce apoptosis. Here, we show that Aspergillus nidulans AifA encoding the apoptosis-inducing factor (AIF)-like mitochondrial oxidoreductase plays a role in the function of the mitochondrial Complex I. Additionally, we demonstrated that ndeA-B and ndiA encode external and internal alternative NADH… CONTINUE READING

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