The roles of signaling pathways in regulating kidney development.

Abstract

The development of mammalian kidney is a complex process. The reciprocal inductive interactions between epithelial cells and metanephric mesenchymal cells determine cell fates including proliferation, growth, apoptosis, and eventually contribute to the formation of an intact kidney. Multiple signaling pathways, including the GDNF/Ret, Wnt and BMP signaling… (More)
DOI: 10.16288/j.yczz.2015.01.001

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