The roles of neuronal and glial precursors in overcoming chondroitin sulfate proteoglycan inhibition.

@article{Ketschek2012TheRO,
  title={The roles of neuronal and glial precursors in overcoming chondroitin sulfate proteoglycan inhibition.},
  author={Andrea R Ketschek and C. Haas and Gianluca Gallo and Itzhak Fischer},
  journal={Experimental neurology},
  year={2012},
  volume={235 2},
  pages={627-37}
}
The extension of axons through the major inhibitory component of the glial scar, chondroitin sulfate proteoglycans (CSPGs), remains a key obstacle for regeneration following spinal cord injury (SCI). We have previously shown that transplants composed of neuronal and glial restricted precursors (NRP and GRP respectively) promote regeneration and connectivity in the injured spinal cord (Bonner et al., 2010, 2011), however, little is known about the properties of these precursors at a cellular… CONTINUE READING
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