The roles of miR-200c in colon cancer and associated molecular mechanisms

@article{Chen2014TheRO,
  title={The roles of miR-200c in colon cancer and associated molecular mechanisms},
  author={Jianmei Chen and Weining Wang and Yangde Zhang and Tiehui Hu and Yuxiang Chen},
  journal={Tumor Biology},
  year={2014},
  volume={35},
  pages={6475-6483}
}
The expression of miR-200c has been widely reported to be elevated in tumor tissues and sera of patients with colorectal cancer (CRC) and has been found to correlate with poor prognosis. However, how miR-200c regulates the apoptosis, survival, invasion, metastasis, and tumor growth in colon cancer cells remains to be fully elucidated. This study seeks to further investigate the role of miR-200c in colon cancer development. The expression of miR-200c in tumor and peritumoral tissues of 101 colon… CONTINUE READING
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