The roles of heterogeneous nuclear ribonucleoproteins (hnRNP) in RNA metabolism.

@article{Weighardt1996TheRO,
  title={The roles of heterogeneous nuclear ribonucleoproteins (hnRNP) in RNA metabolism.},
  author={Florian Weighardt and Giuseppe Biamonti and Silvano Riva},
  journal={BioEssays : news and reviews in molecular, cellular and developmental biology},
  year={1996},
  volume={18 9},
  pages={747-56}
}
In eukaryotic cells, messenger RNAs are formed by extensive post-transcriptional processing of primary transcripts, assembled with a large number of proteins and processing factors in ribonucleoprotein complexes. The protein moiety of these complexes mainly constitutes a class of about 20 major polypeptides called heterogeneous nuclear ribonucleoproteins or hnRNPs. The function and the mechanism of action of hnRNPs is still not fully understood, but the identification of RNA binding domains and… CONTINUE READING