The roles of extracellular DNA in the structural integrity of extracellular polymeric substance and bacterial biofilm development.

@article{Das2013TheRO,
  title={The roles of extracellular DNA in the structural integrity of extracellular polymeric substance and bacterial biofilm development.},
  author={Theerthankar Das and Shama Sehar and Mike Manefield},
  journal={Environmental microbiology reports},
  year={2013},
  volume={5 6},
  pages={778-86}
}
Bacteria adhere to natural and engineered surfaces and develop into mature biofilms encased in self-produced extracellular polymeric substances (EPSs). EPS consists of polysaccharides, proteins, metabolites and extracellular DNA (eDNA). Extracellular DNA release by bacteria is mediated by both quorum-sensing (QS)-dependent and -independent mechanisms. Quorum-sensing-independent mechanisms are responsible for basal levels of eDNA release, whereas QS-dependent mechanisms control the production of… CONTINUE READING
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