The roles of different porcine cytochrome P450 enzymes and cytochrome b5A in skatole metabolism.

@article{Wiercinska2012TheRO,
  title={The roles of different porcine cytochrome P450 enzymes and cytochrome b5A in skatole metabolism.},
  author={P Wiercinska and Yanping Lou and E. James Squires},
  journal={Animal : an international journal of animal bioscience},
  year={2012},
  volume={6 5},
  pages={834-45}
}
Boar taint is the unfavourable odour and taste from pork fat, which results in part from the accumulation of skatole (3-methylindole, 3MI). The key enzymes in skatole metabolism are thought to be cytochrome P450 2E1 (CYP2E1) and cytochrome 2A (CYP2A); however, the cytochrome P450 (CYP450) isoform responsible for the production of the metabolite 6-hydroxy-3-methylindole (6-OH-3MI, 6-hydroxyskatole), which is thought to be involved in the clearance of skatole, has not been established… CONTINUE READING
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A review of the welfare consequences of surgical castration in piglets and the evaluation of non - surgical methods

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