The roles of S1 RNA-binding domains in Rrp5's interactions with pre-rRNA.


RNA-binding proteins mediate the function of all RNAs. Since few distinct RNA-binding domains (RBDs) exist, with most RBDs contacting only a few nucleotides, RNA-binding proteins often combine multiple RNA-binding motifs to achieve a higher affinity and selectivity for their targets. Rrp5, a ribosome assembly factor essential for both 40S and 60S ribosome… (More)
DOI: 10.1261/rna.2458811


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