The roles of IL-10 and TGF-beta in controlling IL-4 and IFN-gamma production during experimental Fasciola hepatica infection.

@article{Flynn2008TheRO,
  title={The roles of IL-10 and TGF-beta in controlling IL-4 and IFN-gamma production during experimental Fasciola hepatica infection.},
  author={Robin J Flynn and Grace M Mulcahy},
  journal={International journal for parasitology},
  year={2008},
  volume={38 14},
  pages={1673-80}
}
Hosts infected with Fasciola hepatica experience immunosuppression during the acute and chronic phases of the disease. This immunosuppression may allow parasite survival in the face of an ongoing immune response. In bovine hosts early IL-4 and continued IgG1 production is one of the few remaining features of the characteristic type 0/2 helper (Th0/2… CONTINUE READING