The roles of HLH transcription factors in epithelial mesenchymal transition and multiple molecular mechanisms

Abstract

Epithelial-to-mesenchymal transition (EMT) is presently recognized as an important event and the initiating stage for tumor invasion and metastasis. Several EMT inducers have been identified, among which the big family of helix–loop–helix (HLH) transcription factors are rising as a novel and promising family of proteins in EMT mediation, such as Twist1… (More)
DOI: 10.1007/s10585-013-9621-6

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