The roles of Drosophila cyclins A and B in mitotic control.

Abstract

We have cloned, sequenced, and characterized the expression of a Drosophila cyclin B gene. The independent evolutionary conservation of A- and B-type cyclins implies that they have distinct roles. Indeed, in mutant embryos deficient in cyclin A, cells that accumulate only cyclin B do not enter mitosis. Thus, in vivo, cyclin B is not sufficient for mitosis… (More)

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Cite this paper

@article{Lehner1990TheRO, title={The roles of Drosophila cyclins A and B in mitotic control.}, author={C{\'e}dric Lehner and Patrick H O'Farrell}, journal={Cell}, year={1990}, volume={61 3}, pages={535-47} }