The role of whole brain radiation therapy in the management of melanoma brain metastases

@inproceedings{Dyer2014TheRO,
  title={The role of whole brain radiation therapy in the management of melanoma brain metastases},
  author={Michael A. Dyer and Nils D. Arvold and Y Chen and Nancy E Pinnell and Timur Mitin and Eudocia Quant Lee and Frank Stephen Hodi and Nageatte Ibrahim and Stephanie E. Weiss and Paul J. Kelly and Scott R. Floyd and Anand Mahadevan and Brian M. Alexander},
  booktitle={Radiation oncology},
  year={2014}
}
BACKGROUND Brain metastases are common in patients with melanoma, and optimal management is not well defined. As melanoma has traditionally been thought of as "radioresistant," the role of whole brain radiation therapy (WBRT) in particular is unclear. We conducted this retrospective study to identify prognostic factors for patients treated with stereotactic radiosurgery (SRS) for melanoma brain metastases and to investigate the role of additional up-front treatment with whole brain radiation… CONTINUE READING