The role of white matter damage in late onset bipolar disorder.

@article{Besga2011TheRO,
  title={The role of white matter damage in late onset bipolar disorder.},
  author={Ariadna Besga and M{\'o}nica Mart{\'i}nez-Cengotitabengoa and Itxaso Gonz{\'a}lez-Ortega and Miguel Gutierrez and Sara Barbeito and A. Gonzalez-Pinto},
  journal={Maturitas},
  year={2011},
  volume={70 2},
  pages={
          160-3
        }
}
Bipolar disorder in elderly is probably heterogenous and the age of onset has been considered to be a potential clinical marker of heterogeneity for this disease. Early- and late-onset bipolar disorders share symptoms, but it is not clear whether they have different aetiologies and vulnerabilities. In bipolar disorder one of the most frequent neuroimaging finding is the white matter hyperintensities (WMHs). The disruption caused by WMHs in the connectivity between structures related to mood… CONTINUE READING
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