The role of vitamin D in reducing cancer risk and progression

  title={The role of vitamin D in reducing cancer risk and progression},
  author={D. Feldman and A. Krishnan and S. Swami and E. Giovannucci and B. J. Feldman},
  journal={Nature Reviews Cancer},
  • D. Feldman, A. Krishnan, +2 authors B. J. Feldman
  • Published 2014
  • Medicine
  • Nature Reviews Cancer
  • Vitamin D is not really a vitamin but the precursor to the potent steroid hormone calcitriol, which has widespread actions throughout the body. Calcitriol regulates numerous cellular pathways that could have a role in determining cancer risk and prognosis. Although epidemiological and early clinical trials are inconsistent, and randomized control trials in humans do not yet exist to conclusively support a beneficial role for vitamin D, accumulating results from preclinical and some clinical… CONTINUE READING
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