The role of virus-specific CD4+ T cells in the control of Epstein-Barr virus infection.

@article{Mautner2012TheRO,
  title={The role of virus-specific CD4+ T cells in the control of Epstein-Barr virus infection.},
  author={Josef Mautner and Georg W. Bornkamm},
  journal={European journal of cell biology},
  year={2012},
  volume={91 1},
  pages={31-5}
}
Epstein-Barr virus (EBV) establishes lifelong persistent infections in humans and has been implicated in the pathogenesis of several human malignancies. Protective immunity against EBV is mediated by T cells, as indicated by an increased incidence of EBV-associated malignancies in immunocompromised patients, and by the successful treatment of EBV-associated post-transplant lymphoproliferative disease (PTLD) in transplant recipients by the infusion of polyclonal EBV-specific T cell lines. To… CONTINUE READING

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References

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Showing 1-10 of 39 references

Epstein-Barr virus

  • A. B. Rickinson, E. Kieff
  • 2007
Highly Influential
5 Excerpts

nuclear antigen 1 evades direct immune recognition by CD4+ T helper cells

  • A. erlo, R. Turrini, +7 authors A. Rosato
  • Eur. J. Immunol
  • 2010

Allogeneic cytotoxic T cell therapy for EBV-positive post transplant lymphoproliferative disease: results of a phase II multicentre clinical trial

  • T. Haque, G. M. Wilkie, +7 authors C Bellamy
  • Blood 110,
  • 2007
2 Excerpts

Epstein-Barr virus and its replication

  • E. ieff, A. B. Rickinson
  • 2007

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