The role of urokinase in vascular cell migration and in regulation of growth and branching of capillaries


The urokinase system, represented by a plasminogen activator of urokinase type (urokinase, uPA), urokinase receptor (uPAR), and inhibitors of plasminogen activator (PAI-1 and PAI-2), plays an important role in the regulation of vascular wall functioning. Urokinase signaling initiates proteolytic cascade and degradation of the extracellular matrix; and also… (More)
DOI: 10.1134/S1990519X16010089


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