The role of transforming growth factor-β1 in airway inflammation of childhood asthma.

@article{Gagliardo2013TheRO,
  title={The role of transforming growth factor-β1 in airway inflammation of childhood asthma.},
  author={Rosalia Gagliardo and Pascal Chanez and Mark Gjomarkaj and Stefania La Grutta and Adriana Bonanno and Angela Marina Montalbano and Caterina Di Sano and Giusy Daniela Albano and Delphine Gras and Giulia Anzalone and Loredana Riccobono and Mirella Profita},
  journal={International journal of immunopathology and pharmacology},
  year={2013},
  volume={26 3},
  pages={
          725-38
        }
}
TGF-beta-targeting structural and inflammatory cells has been implicated in the mechanisms leading to the inflammatory and restructuring processes in asthma, suggesting an impact of TGF-beta1 signaling on the development and persistency of this disease. We investigated the potential early involvement of TGF-beta1 activity in the immunological and molecular mechanisms underlying progression of inflammation in childhood asthma. We evaluated the levels of TGF-beta1 in induced sputum supernatants… CONTINUE READING
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  • 2015

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  • International journal of clinical and experimental pathology
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VIEW 1 EXCERPT
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References

Publications referenced by this paper.
SHOWING 1-10 OF 33 REFERENCES

Noninvasive markers of airway inflammation in asthma.

  • Clinical and translational science
  • 2009
VIEW 8 EXCERPTS
HIGHLY INFLUENTIAL

Standardisation of spirometry.

  • The European respiratory journal
  • 2005
VIEW 4 EXCERPTS
HIGHLY INFLUENTIAL

Clinical and biological heterogeneity in children with moderate asthma

S La Grutta, R Gagliardo, +5 authors AM. Vignola
  • Am J Respir Crit Care Med
  • 2003
VIEW 4 EXCERPTS
HIGHLY INFLUENTIAL

Chronic obstructive pulmonary disease and neutrophil infiltration : role of cigarette smoke and cyclooxygenase products

M Profita, A Sala, A Bonanno
  • Am J Physiol Lung Cell Mol Physiol
  • 2010

Activation of TGF - beta / Smad 2 asthma

H Sagara, T Okada, +4 authors A Nakao
  • Thorax
  • 2005