The role of transferrin and ferritin in the fetal-maternal-placental unit.

@article{Okuyama1985TheRO,
  title={The role of transferrin and ferritin in the fetal-maternal-placental unit.},
  author={Teruaki Okuyama and Toshiyasu Tawada and Hiroshi Furuya and Claude A. Villee},
  journal={American journal of obstetrics and gynecology},
  year={1985},
  volume={152 3},
  pages={344-50}
}
The rapidly growing human fetus requires a large supply of iron, which is obtained from the iron stores of the mother. Iron is transported from mother to fetus against a concentration gradient. The placenta plays a key role in regulating the supply of iron in the fetus. In both anemic and nonanemic patients serum ferritin levels decreased and total iron-binding capacity increased as gestation progressed. The total iron-binding capacity is higher in maternal than in umbilical cord blood at… CONTINUE READING