The role of transcription factors Sp1 and YY1 in proximal promoter region in initiation of transcription of the mu opioid receptor gene in human lymphocytes.

@article{Li2008TheRO,
  title={The role of transcription factors Sp1 and YY1 in proximal promoter region in initiation of transcription of the mu opioid receptor gene in human lymphocytes.},
  author={Hui Li and Han Liu and Zimei Wang and Xinhua Liu and Liyuan Guo and Lijun Huang and Libo Gao and Michael A. Mcnutt and Gang Li},
  journal={Journal of cellular biochemistry},
  year={2008},
  volume={104 1},
  pages={237-50}
}
Although previous studies have shown that the mechanism of the lymphocyte mu opioid receptor (MOR) gene expression was distinctly different from that in the central nervous system, and is involved in several disparate aspects of the immune response, its precise molecular mechanism is still undefined. In this study, we analyzed the proximal promoter region of the MOR gene in lymphocytes to identify the influences of potential trans-acting factors in activating the initiation of the expression of… CONTINUE READING