The role of total body irradiation in the conditioning of patients receiving haploidentical stem cell transplantation.

Abstract

BACKGROUND Nearly 40% of patients requiring a hematopoietic stem cell transplant lack a suitable donor. However, virtually all these patients have a potential family donor with whom they share one HLA haplotype. METHODS We report the rationale for making hematopoietic stem cell transplantation from haploidentical related donors feasible, as well as the… (More)

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