[The role of thromboxane A2 and prostacyclin in the pathogenesis of diabetes mellitus in children and adolescents].

Abstract

The follow-up of children and adolescents (n-41) suffering from insulin-dependent diabetes mellitus has demonstrated that the increase of the thromboxane/prostacyclin ratio pointing to the derangement of microcirculatory regulation occurs during the decompensation phase of the disease and is a risk factor of the development of diabetic complications. The revealed disorders of arachidonic acid metabolism may be one of the causes of the tendency towards decrease of pulse arterial pressure in grave diabetes mellitus.

Cite this paper

@article{Vakhrusheva1991TheRO, title={[The role of thromboxane A2 and prostacyclin in the pathogenesis of diabetes mellitus in children and adolescents].}, author={L. L. Vakhrusheva and Iu A Kniazev and Maria I Martynova and L. B. Pirogova}, journal={Pediatrii︠a︡}, year={1991}, volume={2}, pages={18-22} }