The role of the trehalose system in regulating the maltose regulon of Escherichia coli.

@article{Decker1999TheRO,
  title={The role of the trehalose system in regulating the maltose regulon of Escherichia coli.},
  author={Katja Decker and Fritz Gerhardt and Winfried Boos},
  journal={Molecular microbiology},
  year={1999},
  volume={32 4},
  pages={777-88}
}
The maltose regulon consists of 10 genes encoding an ABC transporter for maltose and maltodextrins as well as enzymes necessary for their degradation. MalK, the energy-transducing subunit of the transport system, acts phenotypically as a repressor of MalT, the transcriptional activator of the mal genes. Using MacConkey maltose indicator plates we isolated an insertion mutation that strongly reduced the repressing effect of overproduced MalK. The insertion had occurred in treR encoding the… CONTINUE READING

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