The role of the thymus in development of necrotizing arteritis in transgenic rats carrying the env-pX gene of human T-cell leukemia virus type-I.

Abstract

Necrotizing arteritis mimicking polyarteritis nodosa occurred in transgenic rats carrying the env-pX gene of human T-cell leukemia virus type I. To investigate the pathogenesis of necrotizing arteritis in these rats (env-pX rats), adoptive transfers of spleen cells and bone marrow cells were done from env-pX rats before they developed arteritis to… (More)

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@article{Fugo2002TheRO, title={The role of the thymus in development of necrotizing arteritis in transgenic rats carrying the env-pX gene of human T-cell leukemia virus type-I.}, author={Kazunori Fugo and Akihiro Ishizu and Hitoshi Ikeda and Hiroko Hayase and Toshiaki Sugaya and Masato Higuchi and Muneharu Tsuji and Asami Abe and Akira Suzuki and M. Shibata and Toshiyuki Takahashi and Takashi Yoshiki}, journal={The American journal of pathology}, year={2002}, volume={161 3}, pages={755-61} }