The role of the sarcolemma action potential in fatigue.

  title={The role of the sarcolemma action potential in fatigue.},
  author={Andrew J. Fuglevand},
  journal={Advances in experimental medicine and biology},
A prevalent feature of neuromuscular fatigue is a decline in the extracellularly recorded myoelectric signal. One factor that could underlie this change is a decrease in the amplitude of the sarcolemmal action potential. Based on observed reductions in action potential amplitude without effect on force, it has been argued that changes in the action potential during sustained activity would be unlikely to contribute to fatigue. However, those observations were primarily from experiments in which… CONTINUE READING