The role of the retinal pigment epithelium: Topographical variation and ageing changes

@article{Boulton2001TheRO,
  title={The role of the retinal pigment epithelium: Topographical variation and ageing changes},
  author={Mike Boulton and Pierrette Dayhaw-Barker},
  journal={Eye},
  year={2001},
  volume={15},
  pages={384-389}
}
The retinal pigment epithelium (RPE) is a single layer of post-mitotic cells, which functions both as a selective barrier to and a vegetative regulator of the overlying photoreceptor layer, thereby playing a key role in its maintenance. Through the expression and activity of specific proteins, it regulates the transport of nutrients and waste products to and from the retina, it contributes to outer segment renewal by ingesting and degrading the spent tips of photoreceptor outer segments, it… CONTINUE READING