The role of the reticuloendothelial system in the host reaction to neoplasia.

@article{Old1961TheRO,
  title={The role of the reticuloendothelial system in the host reaction to neoplasia.},
  author={Lloyd J. Old and Baruj Benacerraf and Donald A. Clarke and Elizabeth A. Carswell and Elisabeth Stockert},
  journal={Cancer research},
  year={1961},
  volume={21},
  pages={
          1281-300
        }
}
The fundamental questions to be dealt with in studies of the cancer process can be broadly divided into two general categories. One involves the events which lead to the origin of the cancer cell, encompassing those int imate intraeellular alterations induced by virus, chemical, or physical eareinogen which lead to the formation of cells with neoplastic potential. The other process involves the possible host reaction to the existent tumor or to the agents responsible for its origin. I t is with… 
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