The role of the renin-angiotensin-aldosterone system in preeclampsia: genetic polymorphisms and microRNA.

@article{Yang2013TheRO,
  title={The role of the renin-angiotensin-aldosterone system in preeclampsia: genetic polymorphisms and microRNA.},
  author={Jinlong Yang and Jianyu Shang and Suli Zhang and Hao Li and Huirong Liu},
  journal={Journal of molecular endocrinology},
  year={2013},
  volume={50 2},
  pages={R53-66}
}
The compensatory alterations in the rennin-angiotensin-aldosterone system (RAAS) contribute to the salt-water balance and sufficient placental perfusion for the subsequent well-being of the mother and fetus during normal pregnancy and is characterized by an increase in almost all the components of RAAS. Preeclampsia, however, breaks homeostasis and leads to a disturbance of this delicate equilibrium in RAAS both for circulation and the uteroplacental unit. Despite being a major cause for… CONTINUE READING