The role of the opioid system in alcohol dependence.

@article{Nutt2014TheRO,
  title={The role of the opioid system in alcohol dependence.},
  author={David J Nutt},
  journal={Journal of psychopharmacology},
  year={2014},
  volume={28 1},
  pages={
          8-22
        }
}
The role of the brain opioid system in alcohol dependence has been the subject of much research for over 25 years. This review explores the evidence: firstly describing the opioid receptors in terms of their individual subtypes, neuroanatomy, neurophysiology and ligands; secondly, summarising emerging data from specific neurochemical, behavioural and neuroimaging studies, explaining the characteristics of addiction with a focus on alcohol dependence and connecting the opioid system with alcohol… CONTINUE READING

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