The role of the metal-bound N–H functionality in Noyori-type molecular catalysts

@article{Dub2018TheRO,
  title={The role of the metal-bound N–H functionality in Noyori-type molecular catalysts},
  author={Pavel A. Dub and John C. Gordon},
  journal={Nature Reviews Chemistry},
  year={2018},
  volume={2},
  pages={396-408}
}
Noyori-type catalysts have found numerous applications in research and industrial settings. The central mechanistic component of such catalysts is a metal centre coordinated to a N–H moiety. This amino moiety has traditionally been thought to participate directly in catalytic reactions by serving as a H+ donor, with the resulting amido group then serving as a H+ acceptor. This traditional understanding has been supplanted by more recent studies that instead suggest that the N–H group(s) (or N… Expand
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