The role of the medial prefrontal cortex of rats in short-term memory functioning: further support for involvement of cholinergic, rather than dopaminergic mechanisms

@article{Broersen1995TheRO,
  title={The role of the medial prefrontal cortex of rats in short-term memory functioning: further support for involvement of cholinergic, rather than dopaminergic mechanisms},
  author={Laus M. Broersen and Rob P. W. Heinsbroek and Jan P.C. de Bruin and Harry B. M. Uylings and Berend Olivier},
  journal={Brain Research},
  year={1995},
  volume={674},
  pages={221-229}
}
The putative involvement of the dopaminergic innervation of the medial part of the prefrontal cortex (PFC) in short-term memory functioning was investigated by evaluating the effects of local infusions of dopaminergic drugs into the ventral part of the medial PFC of rats in an operant delayed-matching-to-position (DMTP) task. Two separate groups of rats were tested after bilateral microinfusion of several doses of either the dopamine receptor agonist apomorphine (APO) or the dopamine receptor… 
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Evaluating the effects of local infusions of dopaminergic drugs into the medial prefrontal cortex of rats in an operant delayed-matching-to-position (DMTP) task supports a direct involvement of the rat mPFC in short-term memory processes, although they implicate cholinergic rather than dopaminerential mechanisms in this function.
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