The role of the lysophospholipid sphingosine 1-phosphate in immune cell biology

@article{Wenckstern2006TheRO,
  title={The role of the lysophospholipid sphingosine 1-phosphate in immune cell biology},
  author={Henrik von Wenckstern and Karsten Zimmermann and Burkhard Kleuser},
  journal={Archivum Immunologiae et Therapiae Experimentalis},
  year={2006},
  volume={54},
  pages={239-251}
}
Sphingosine 1-phosphate (S1P) has been shown to be a bioactive lipid mediator intimately involved in mediating a variety of immunological processes. In particular, S1P regulates lymphocyte cell trafficking between the lymphatic system and the blood. The lysophospholipid signals mainly through five related G protein-coupled receptor subtypes, termed S1P1 to… CONTINUE READING