The role of the liver in exocrine pancreatic disease.

@article{Braganza1988TheRO,
  title={The role of the liver in exocrine pancreatic disease.},
  author={Joan Marie Braganza},
  journal={International journal of pancreatology : official journal of the International Association of Pancreatology},
  year={1988},
  volume={3 Suppl 1},
  pages={
          S19-42
        }
}
Heightened, but unmitigated, free radical activity within the liver, and the intrinsic bioactivity of certain FROPs and drug metabolites, would rationalise those liver aberrations that cannot be explained on the basis of enzyme induction. Thus the increased amounts of copper in bile suggest heightened production of non-biological reactive intermediates--perhaps derived from halogenated hydrocarbons [29]--and the consequent utilisation of glutathione; because it is known that copper in bile is… CONTINUE READING