The role of the lipogenic pathway in the development of hepatic steatosis.

  title={The role of the lipogenic pathway in the development of hepatic steatosis.},
  author={Catherine Postic and Julien Girard},
  journal={Diabetes & metabolism},
  volume={34 6 Pt 2},
Non-alcoholic fatty liver disease (NAFLD) represents a wide spectrum of diseases, ranging from simple fatty liver (hepatic steatosis) through steatosis with inflammation and necrosis to cirrhosis. NAFLD, which is strongly associated with obesity, insulin resistance and type 2 diabetes, is now well recognized as being part of the metabolic syndrome. The metabolic pathways leading to the development of hepatic steatosis are multiple, including enhanced non-esterified fatty acid release from… CONTINUE READING
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