The role of the high-density lipoprotein receptor SR-BI in cholesterol metabolism.

@article{Trigatti2000TheRO,
  title={The role of the high-density lipoprotein receptor SR-BI in cholesterol metabolism.},
  author={Bernardo Louis Trigatti and Attilio A Rigotti and Monty Krieger},
  journal={Current opinion in lipidology},
  year={2000},
  volume={11 2},
  pages={123-31}
}
The HDL receptor scavenger receptor class B type I (SR-BI), which mediates selective HDL cholesterol uptake, plays a role in murine HDL metabolism, reverse cholesterol transport and whole-body cholesterol homeostasis. SR-BI is found in the liver, where its expression is regulated by estrogen, dietary cholesterol and fat, and controls murine plasma HDL cholesterol levels and bile cholesterol secretion. SR-BI is also highly expressed in rodent steroidogenic cells, where it facilitates cholesterol… CONTINUE READING
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