The role of the gut microbiota in energy metabolism and metabolic disease.

@article{Cani2009TheRO,
  title={The role of the gut microbiota in energy metabolism and metabolic disease.},
  author={Patrice D Cani and Nathalie M. Delzenne},
  journal={Current pharmaceutical design},
  year={2009},
  volume={15 13},
  pages={
          1546-58
        }
}
Obesity is now classically characterized by a cluster of several metabolic disorders, and by a low grade inflammation. The evidence that the gut microbiota composition can be different between healthy and or obese and type 2 diabetic patients has led to the study of this environmental factor as a key link between the pathophysiology of metabolic diseases and the gut microbiota. Several mechanisms are proposed linking events occurring in the colon and the regulation of energy metabolism, such as… Expand

Paper Mentions

Interventional Clinical Trial
Background : There is a plausible relationship between microbial gut and insulin resistance. Intervention to prevent insulin resistance by modifying the microbial gut has been… Expand
ConditionsInsulin Resistance, Obesity
InterventionDietary Supplement, Drug
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TLDR
Short-chain, saturated, and polyunsaturated fatty acids have an impact with respect to gut microbiota and health, presenting central and systemic effects associated with the genesis of obesity. Expand
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Involvement of the gut microbiota in the development of low grade inflammation associated with obesity: focus on this neglected partner.
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