The role of the gastric afferent vagal nerve in ghrelin-induced feeding and growth hormone secretion in rats.

@article{Date2002TheRO,
  title={The role of the gastric afferent vagal nerve in ghrelin-induced feeding and growth hormone secretion in rats.},
  author={Yukari Date and Noboru Murakami and Koji Toshinai and Shigeru Matsukura and Akira Niijima and Hisayuki Matsuo and Kenji Kangawa and Masamitsu Nakazato},
  journal={Gastroenterology},
  year={2002},
  volume={123 4},
  pages={
          1120-8
        }
}
BACKGROUND & AIMS Visceral sensory information is transmitted to the brain through the afferent vagus nerve. Ghrelin, a peptide primarily produced in the stomach, stimulates both feeding and growth hormone (GH) secretion. How stomach-derived ghrelin exerts these central actions is still unknown. Here we determined the role of the gastric afferent vagal nerve in ghrelin's functions. METHODS Food intake and GH secretion were examined after an administration of ghrelin intravenously (IV) to rats… 

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