The role of the dorsal striatum in choice impulsivity

@article{Kim2018TheRO,
  title={The role of the dorsal striatum in choice impulsivity},
  author={Baeksun Kim and Heh-In Im},
  journal={Annals of the New York Academy of Sciences},
  year={2018},
  volume={1451}
}
  • Baeksun Kim, Heh-In Im
  • Published 17 September 2018
  • Medicine, Psychology
  • Annals of the New York Academy of Sciences
It has long been recognized that the dorsal striatum is an essential brain region for control of action selection based on action–outcome contingency learning, particularly when the available actions are bound to rewarding outcomes. In principle, intertemporal choice in the delay‐discounting task—a validated measure of choice impulsivity—involves reward‐associated actions that require the recruitment of the dorsal striatum. Here, we conjecture about ways the dorsal striatum is involved in… 
Striatal bases of temporal discounting in early adolescents
TLDR
Engagement of the striatum in early adolescence is examined to provide an important first glimpse at the distributed neural systems underlying economic choice and trait-like individual differences in impulsivity in the early years of adolescence, setting the stage for prospective-longitudinal and intervention research.
Dopamine axons in dorsal striatum encode contralateral visual stimuli and choices
TLDR
In a visual decision task, dopamine axons in the dorsomedial striatum signaled stimuli presented contralaterally to the recorded hemisphere, as well as the onset of rewarded actions, which contribute to the characterization of region-specific dopaminergic signaling in the striatum and highlight a role in stimulus-action association learning.
Experience-related remapping of temporal encoding by striatal ensembles
TLDR
Recording from medium-spiny neurons in the dorsal striatum of mice shows how MSN ensembles can evolve with experience, and finds that time-related ramping activity and response-related activity increased with more experience.
Altered effective connectivity of the reward network during an incentive processing task in adults with alcohol use disorder.
TLDR
Individuals with AUD have disrupted EC in both instrumentally-driven and automatized cortico-striatal reward circuits during non-alcohol reward feedback, and results point to disrupted corticostriatalEC in both "top-down" and "bottom-up" pathways among individuals with AUD.
Temporal discounting in adolescents and adults with Tourette syndrome
TLDR
It is speculated that adolescents might show reduced discounting due to improved inhibitory functions that also affect choice impulsivity and/or the developmental trajectory of executive control functions.
Temporal discounting in adolescents and adults with Tourette syndrome
TLDR
Adults and adolescents with Tourette syndrome might show attenuated discounting due to improved inhibitory functions that also affect choice impulsivity and/or the developmental trajectory of executive control functions, according to neural models of temporal discounting and dopaminergic alterations.
Pubertal Testosterone Correlates with Adolescent Impatience and Dorsal Striatal Activity
TLDR
Investigating task-related impatience of boys between 10 and 15 years of age using an intertemporal choice task combined with measures of functional magnetic resonance imaging and hormonal assessment shows that testosterone specifically modulates the dorsal, not ventral, striatal pathway.
Network failures: When incentives trigger impulsive responses
TLDR
It is reported that group‐specific incentive salience plays a critical role in modulating impulsivity in SDIs since drug‐related incentives specifically increased premature responding and shifted task modulation away from the dorsal striatal network to the cingulo‐opercular network.
Morphine exposure alters Fos expression in a sex-, age-, and brain region-specific manner during adolescence.
TLDR
It is determined that the neural response to acute morphine is highly dependent on adolescent age, sex, and brain region, and this data suggest that heterogeneity in the consequences of adolescent opioid exposure may be due to age- and sex-specific developmental profiles in individual reward processing regions.
Alterations in NMDAR-mediated signaling within the laterodorsal tegmental nucleus are associated with prenatal nicotine exposure
TLDR
It is hypothesized that NMDA-mediated signaling changes within LDT neurons following PNE treatment would result in reductions of excitatory cholinergic modulatory tone in target brain regions, which would be expected to contribute to the behavioral deficits found among these individuals.
...
1
2
3
4
...

References

SHOWING 1-10 OF 157 REFERENCES
Dopaminergic Lesions of the Dorsolateral Striatum in Rats Increase Delay Discounting in an Impulsive Choice Task
TLDR
Data reveal a contribution of dopaminergic inputs to the dorsolateral striatum on impulsive choice behavior, and provide new insights into neural substrates underlying discounting behaviors.
The Role of the Dorsal Striatum in Reward and Decision-Making
TLDR
Key evidence suggests that the dorsal striatum contributes directly to decision-making, especially to action selection and initiation, through the integration of sensorimotor, cognitive, and motivational/emotional information within specific corticostriatal circuits involving discrete regions of striatum.
Dopamine, Corticostriatal Connectivity, and Intertemporal Choice
TLDR
Results indicate that raising cortical dopamine levels attenuates impulsive choice by changing corticostriatal function.
Dissociable frontostriatal white matter connectivity underlies reward and motor impulsivity
TLDR
The findings suggest that structural connectivity can is associated with a large amount of behavioral variation; different types of impulsivity are driven by dissociable frontostriatal neural circuitry.
Triple Dissociation of Information Processing in Dorsal Striatum, Ventral Striatum, and Hippocampus on a Learned Spatial Decision Task
TLDR
A comparative methodology is developed in order to use a comparative methodology and apply the same analyses to all three structures and suggests that the different roles these structures play are due to differences in information-processing mechanisms.
Action Selection and Action Value in Frontal-Striatal Circuits
TLDR
Examination of neural activity showed that the representation of the selected action was stronger in lateral prefrontal cortex (lPFC), and occurred earlier in the lPFC than it did in the dorsal striatum (dSTR), but the dSTR contains an enriched representation of action value, but it followed frontal cortex in action selection.
Motivational neural circuits underlying reinforcement learning
TLDR
It is shown that both the amygdala and striatum learn and represent expected values in RL tasks and that value representations in the striatum may be inherited, to some extent, from the amygdala.
Resting-State Functional Connectivity Predicts Impulsivity in Economic Decision-Making
TLDR
It is suggested that resting-state functional organization of the human brain may be a biomarker of impulsivity and can predict economic decision-making behavior.
Serotonin Differentially Regulates Short- and Long-Term Prediction of Rewards in the Ventral and Dorsal Striatum
TLDR
The results suggest that serotonin controls the time scale of reward prediction by differentially regulating activities within the striatum.
Dopaminergic function and intertemporal choice
TLDR
In subjects with Parkinson’s disease and dopamine medication-induced behavioral addictions, temporal discounting is further correlated with greater dopaminergic terminal function in the anterior putamen, suggesting that dopamine-mediated devaluation of larger delayed rewards may drive choice preferences.
...
1
2
3
4
5
...