The role of the cytoskeleton in the formation of gap junctions by Connexin 30.

@article{Qu2009TheRO,
  title={The role of the cytoskeleton in the formation of gap junctions by Connexin 30.},
  author={Chunyan Qu and Phyllis Gardner and Iris Schrijver},
  journal={Experimental cell research},
  year={2009},
  volume={315 10},
  pages={1683-92}
}
Mutations in the genes that encode Connexin 26 (GJB2) and Connexin 30 (GJB6) are the most common known cause of hereditary nonsyndromic sensorineural deafness. Cx26 and Cx30 share a similar protein structure, as well as the same expression distribution pattern in the cochlea. Cx26 has different intracellular trafficking properties compared to those of Cx43 and Cx32, whose trafficking manner is consistent with the classical membrane protein secretory pathway. Until now, however, the trafficking… CONTINUE READING
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Mictotubules and actin differentially influence remodeling of connexin43 gap junctions

  • A. Hunter, R. Gourdie
  • FASEB J. 22
  • 2008

A

  • H. B. Zhao, T. Kikuchi
  • Ngezahayo, T.W.White, Gap junctions and cochlear…
  • 2006
1 Excerpt

Gap junctions and cochlear homeostasis

  • P. M. Drüge Traub, K. Willecke
  • J . Membr . Biol .
  • 2006

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