The role of the cytoskeleton in sensing changes in gravity by nonspecialized cells

  title={The role of the cytoskeleton in sensing changes in gravity by nonspecialized cells},
  author={Daan Vorselen and Wouter H. Roos and Fred C. MacKintosh and Gijs J. L. Wuite and Jack J. W. A. van Loon},
  journal={The FASEB Journal},
  pages={536 - 547}
A large body of evidence indicates that single cells in vitro respond to changes in gravity, and that this response might play an important role for physiological changes at the organism level during spaceflight. Gravity can lead to changes in cell proliferation, differentiation, signaling, and gene expression. At first glance, gravitational forces seem too small to affect bodies with the size of a cell. Thus, the initial response to gravity is both puzzling and important for understanding… 

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  • Biology
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology
  • 1999
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  • 2003

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    ASGSB bulletin : publication of the American Society for Gravitational and Space Biology
  • 1989
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