The role of the complement system in innate immunity

  title={The role of the complement system in innate immunity},
  author={H. Rus and C. Cudrici and F. Niculescu},
  journal={Immunologic Research},
  • H. Rus, C. Cudrici, F. Niculescu
  • Published 2005
  • Biology, Medicine
  • Immunologic Research
  • Complement is a major component of innate immune system involved in defending against all the foreign pathogens through complement fragments that participate in opsonization, chemotaxis, and activation of leukocytes and through cytolysis by C5b-9 membrane attack complex. Bacterias and viruses have adapted in various ways to escape the complement activation, and they take advantage of the complement system by using the host complement receptors to infect various cells. Complement activation also… CONTINUE READING
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