The role of the central serotonergic system in pilocarpine-induced seizures: receptor mechanisms.

@article{Janusz1989TheRO,
  title={The role of the central serotonergic system in pilocarpine-induced seizures: receptor mechanisms.},
  author={W. Janusz and Zdzisław Kleinrok},
  journal={Neuroscience research},
  year={1989},
  volume={7 2},
  pages={144-53}
}
Modification of central serotonergic transmission resulted in alterations of pilocarpine convulsive activity in male Wistar rats. Seizure activity was increased after pizotifen injection and the latency period to onset of convulsions was shortened in animals pretreated with mianserine and quipazine. Stimulation of 5-HT1A receptors with 8-hydroxy-di-N,N… CONTINUE READING