The role of the central ghrelin system in reward from food and chemical drugs

@article{Dickson2011TheRO,
  title={The role of the central ghrelin system in reward from food and chemical drugs},
  author={S. Dickson and E. Egecioglu and S. Landgren and K. Skibicka and E. Jerlhag},
  journal={Molecular and Cellular Endocrinology},
  year={2011},
  volume={340},
  pages={80-87}
}
Here we review recent advances that identify a role for the central ghrelin signalling system in reward from both natural rewards (such as food) and artificial rewards (that include alcohol and drugs of abuse). Whereas ghrelin emerged as a stomach-derived hormone involved in energy balance, hunger and meal initiation via hypothalamic circuits, it now seems clear that it also has a role in motivated reward-driven behaviours via activation of the so-called "cholinergic-dopaminergic reward link… Expand
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